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Federal Grant Will Help Marshfield Clinic Researchers Study Effectiveness of Third Dose Vaccines

Friday, November 14th, 2014 -- 8:14 AM

-A $440,000 federal grant will support Marshfield Clinic researchers' study of long-term effectiveness of a third dose of Measles, Mumps and Rubella vaccine, as scientists work to better protect against mumps.

Researchers will work to determine the long-term immune response to a third dose. This is important, given recent mumps outbreaks among highly vaccinated populations in the United States.

This study will continue a study started in 2009-10 in which MCRF enrolled young adults ages 18-24 in a CDC-funded study looking at safety and short-term immune response to a third dose of MMR vaccine. Researchers now will reach out to those same study enrollees to see if their immune response has changed five years later.

In 2006, there was a multi-state mumps outbreak with more than 6,500 reported cases. In 2009-10, another large mumps outbreak occurred in multiple locations in northeastern U.S. with about 3,000 reported cases. This year, mumps outbreaks have been reported in at least four U.S. universities, including UW-Madison.

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